EU drug regulator OKs Novartis' meningitis B shot

LONDON (AP) — Europe's top drug regulator has recommended approval for the first vaccine against meningitis B, made by Novartis AG.

There are five types of bacterial meningitis. While vaccines exist to protect against the other four, none has previously been licensed for type B meningitis. In Europe, type B is the most common, causing 3,000 to 5,000 cases every year.

Meningitis mainly affects infants and children. It kills about 8 percent of patients and leaves others with lifelong consequences such as brain damage.

In a statement on Friday, Andrin Oswald of Novartis said he is "proud of the major advance" the company has made in developing its vaccine Bexsero. It is aimed at children over two months of age, and Novartis is hoping countries will include the shot among the routine ones for childhood diseases such as measles.

Novartis said the immunization has had side effects such as fever and redness at the injection site.

Recommendations from the European Medicines Agency are usually adopted by the European Commission. Novartis also is seeking to test the vaccine in the U.S.

Read More..

Boy, 14, sexually assaults 65-year-old woman at store, authorities say



A 14-year-old California boy was arrested Thursday night in connection with the attempted murder, kidnapping and sexual assault of a 65-year-old woman.


Officers found the woman bound by duct tape in a ditch near Hiddenbrooke Parkway and Interstate Highway 80 around 6 p.m. Thursday, according to the Bay City News Service.


Police said the victim was kidnapped at gunpoint in front of a retail store and was forced to drive to a location five miles away where she was physically and sexually assaulted.


The suspect then fled in the victim's minivan and called one of her family members, demanding money for her safe return.


Detectives located the suspect after he returned to the area. He was found with a replica handgun and the victim's minivan, police said.


The teen has been booked into Solano County Juvenile Hall.


ALSO:

Only 31% of California students are physically fit


Laguna Beach to punish parents for teen drinking


L.A. deputy charged in slaying, faces 75-year term if convicted


-- Wesley Lowery


Follow Wesley Lowery on Twitter and Google+.


Read more


here: http://www.sacbee.com/2012/11/16/4991207/teen-arrested-in-vallejo-elderly.html#storylink=cpy



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Israeli Strike Kills at Least 11, Including Children





GAZA CITY — Israeli forces killed at least 11 people, including several children, in a single airstrike that destroyed a home here on Sunday, as Israel pressed its bombardment of the Gaza Strip for a fifth day, deploying warplanes and naval vessels to pummel the coastal enclave.




The airstrike, which the Israeli military said was meant to kill a Palestinian militant involved in the recent rocket attacks, was the deadliest operation to date and would no doubt weigh on negotiations for a possible cease-fire. Among the dead were five women and four small children, The Associated Press reported, citing a Palestinian health official.


Two media offices were also hit on Sunday, and Prime Minister Benjamin Netanyahu of Israel warned of a “significant” expansion in the onslaught, which has already killed over 50 people, many of them civilians.


Speaking on Sunday from Bangkok, President Obama condemned missile attacks by Palestinian fighters in Gaza and defended Israel’s right to protect itself.


“There’s no country on earth that would tolerate missiles raining down on its citizens from outside its borders,” Mr. Obama said in his first public comments since the violence broke out. “We are fully supportive of Israel’s right to defend itself.”


The president also said that efforts were under way to address Israel’s security concerns and end the violence. “We’re going to have to see what kind of progress we can make in the next 24, 36, 48 hours,” Mr. Obama said.


Even as the diplomacy intensified on Sunday, the attacks continued in Gaza and Israel.


Mr. Netanyahu made his warning as militants in Gaza aimed at least one rocket at Tel Aviv, a day after Israeli forces broadened the attack beyond military targets, bombing centers of government infrastructure in Gaza, including the four-story headquarters of the Hamas prime minister.


“We are exacting a heavy price from Hamas and the terrorist organizations, and the Israel Defense Forces are prepared for a significant expansion of the operation,” Mr. Netanyahu told his cabinet at its routine Sunday meeting, referring directly to the of thousands of reservists who have been called up and the massing of armor on the Gaza border that many analysts have interpreted as preparations for a possible invasion.


“I appreciate the rapid and impressive mobilization of the reservists who have come from all over the country and turned out for the mission at hand,” Mr. Netanyahu said. “Reservist and conscript soldiers are ready for any order they might receive.”


His remarks were reported shortly after a battery of Israel’s Iron Dome defense shield, hastily deployed near Tel Aviv on Saturday in response to the threat of longer-range rockets, intercepted at least one aimed at the city on Sunday, Israeli officials said. It was the latest of several salvos that have illustrated Hamas’s ability to extend the reach of its rocket attacks.


Since Wednesday, when the escalation of the conflict began, Iron Dome has knocked 245 rockets out of the sky, the military said Saturday, while 500 have struck Israel.


The American-financed system is designed to intercept only rockets streaking toward towns and cities and to ignore those likely to strike open ground. But on Sunday a rocket fired from Gaza plowed through the roof of an apartment building in the southern Israeli city of Ashkelon. There were no immediate reports of casualties there.


In Gaza City, the crash of explosions pierced the quiet several times throughout the early morning.


Before the latest deadly strike involving civilians on Sunday, Hamas health officials had said the Palestinian death toll had risen to 53. One of the latest victims was a 52-year-old woman whose house in the eastern part of Gaza City was bombed around lunchtime.


A few hours earlier, a Hamas militant was killed and seven people were wounded in an attack on the Beach Refugee Camp, where Ismail Haniya, the Hamas prime minister, has a home. Those killed on Sunday included three children ages 1 through 5, the health officials said.


In Israel, 3 civilians have died and 63 have been injured. Four soldiers were wounded on Saturday.


The onslaught continued despite talks in Cairo that President Mohamed Morsi of Egypt said Saturday night could soon result in a cease-fire. Mr. Netanyahu said he would consider a comprehensive cease-fire if the launchings from Gaza stopped.


The attack on Mr. Haniya’s office, one of several on government installations, came a day after he hosted his Egyptian counterpart in the same building, a sign of Hamas’s new legitimacy in a radically redrawn Arab world.


Jodi Rudoren and Fares Akram reported from Gaza City. Reporting was contributed by Isabel Kershner, Carol Sutherland and Iritz Pazner Garshowitz from Jerusalem; Tyler Hicks from Gaza, Peter Baker from Bangkok, Alan Cowell from London, Michael Schwirtz from New York and David D. Kirkpatrick and Mayy El Sheikh from Cairo.



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Wii U: New console launches in a sea of gadgets
















NEW YORK (AP) — In the six years since the last major video game system launched, Apple unveiled the iPhone and the iPad, “Angry Birds” invaded smartphones and Facebook reached a billion users. In the process, scores of video game consoles were left to languish in living rooms alongside dusty VCRs and disc players.


On Sunday, Nintendo Co. is launching the Wii U, a game machine designed to appeal both to the original Wii’s casual audience and the hardcore gamers who skip work to be among the first to play the latest “Call of Duty” release. Just like the Wii U’s predecessor, the Wii, which has sold nearly 100 million units worldwide since 2006, the new console’s intended audience “truly is 5 to 95,” says Reggie Fils-Aime, the president of Nintendo of America, the Japanese company’s U.S. arm.













But the Wii U arrives in a new world. Video game console sales have been falling, largely because it’s been so long since a new system has launched. Most people who wanted an Xbox 360, PlayStation 3 or a Wii already have one. Another reason: People in the broad 5-to-95 age range have shifted their attention to games on Facebook, tablet computers and mobile phones.


U.S. video game sales last month, including hardware, software and accessories, totaled $ 755.5 million, according to the research firm NPD Group. In October 2007, the figure stood at $ 1.1 billion.


The Wii U is likely to do well during the holiday shopping season, analysts believe —so well that shoppers may see shortages. But the surge could peter out in 2013. The Wii U is not expected to be the juggernaut that the Wii was in its heyday, according to research firm IHS iSuppli. The Wii outsold its competitors, the Xbox 360 and the PlayStation 3, in its first four years on sale, logging some 79 million units by the end of 2010. By comparison, IHS expects the Wii U to sell 56.7 million in its first four years.


In the age of a million gadgets and lean wallets, the storied game company faces a new challenge: convincing people that they need a new video game system rather than, say, a new iPad.


The Wii U, which starts at $ 300, isn’t lacking in appeal. It allows for “asymmetrical game play,” meaning two people playing the same game can have entirely different experiences depending on whether they use a new tablet-like controller called the GamePad or the traditional Wii remote. The GamePad can also be used to play games without using a TV set, as you would on a regular tablet. And it serves as a fancy remote controller to navigate a TV-watching feature called TVii, which will be available in December.


Nintendo, known for iconic game characters such as Mario, Donkey Kong and Zelda, is expected to sell the consoles quickly in the weeks leading up to the holidays. After all, it’s been six long years and sons, daughters, brothers and sisters are demanding presents. GameStop Corp., the world’s No. 1 video game retailer, said last week that advance orders sold out and it has nearly 500,000 people on its Wii U waitlist.


Even so, it’s a “very, very crowded space in consumer electronics” this holiday season, notes Ben Bajarin, a principal analyst at Creative Strategies who covers gaming.


Apple‘s duo of iPads, the full-size model and a smaller version called the Mini, will be competing for shoppers’ attention. Not to be outdone, Amazon.com Inc. has launched a trove of Kindle tablets and e-readers in time for the holidays. These range from the Paperwhite, a touch-screen e-reader, to the Kindle Fire HD, which features a color screen and can work with a cellular data plan. Then there are the new laptops and cheaper, thinner “ultrabooks” featuring Microsoft’s new Windows 8 operating system —not to mention smartphones from Apple Inc., Samsung and other manufacturers.


Nintendo has to be a cut above the noise here,” Bajarin says.


The Wii U is the first major game console to launch in years, but in some ways Nintendo is merely catching up with the HD trend. Sony Corp. and Microsoft Corp. began selling their own powerful, high-definition consoles six and seven years ago, respectively. Both Sony and Microsoft are expected to unveil new game consoles in 2013.


Baird analyst Colin Sebastian thinks the question is not how well the Wii U will do during the holidays, but how it will fare three and six months later.


Gaming has changed significantly in the past six years, especially when it comes to the type of mass-audience experiences that serve as Nintendo‘s bread and butter. Zynga Inc., the online game company behind Facebook games such as “FarmVille” and “Texas HoldEm Poker,” was founded in 2007. The first “Angry Birds” game, that addictive, quirky distraction that has players flinging cartoon birds at structures hiding smug green pigs launched in late 2009. The first iPad, of course, came out in 2010 —three years after the first iPhone.


Fils-Aime acknowledges that Nintendo competes in the broad entertainment landscape, “minute-by-minute,” for consumers’ time.


“That’s true today and that was true 20 years ago,” he says, adding that Nintendo‘s challenge is communicating to people “what is so fun and appealing about the new system.”


Analysts expect Wii U sales to be brisk over the holidays. Nintendo‘s loyal —some would say, fanatical— fan base has been placing advance orders and will likely keep the systems flying off store shelves well into next year. The classic Mario and Zelda games are a huge part of the appeal, since they can’t be played on any gaming system but Nintendo‘s.


Research firm IHS iSuppli estimates that by the end of the year, people will have snapped up 3.5 million Wii U consoles worldwide, compared with 3.1 million Wii units in the same period through the end of 2006.


After the Wii went on sale, shortages persisted for months. Stores were met with long lines of shoppers trying to get their hands on a Wii as late as July 2007, more than seven months after the system’s launch.


Though supply constraints are expected this time around, Fils-Aime says Nintendo will have more hardware available in the Americas than it had for the Wii’s initial months on the market. The company says it will also replenish retailers more frequently than it did six years ago.


An initial sell-out doesn’t mean the Wii U will be successful over the long term, IHS notes, citing its estimate that the Wii U won’t match the Wii’s sales over time.


Bajarin believes it’s going to take “a little bit of time” for the Wii U’s dual-screen gaming concept to sink in with people. If it proves popular, Nintendo could see even more competition at its hands.


“Technologically, it’s not a leap of the imagination to see Apple, Google, Microsoft do something like this,” he says.


____


Follow Barbara Ortutay on Twitter at https://twitter.com/BarbaraOrtutay


Gadgets News Headlines – Yahoo! News



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Jessica Simpson Shows Off 60-Lb. Weight Loss















11/18/2012 at 03:30 PM EST



Hot mamma alert!

Just more than six months after welcoming daughter Maxwell Drew on May 1 with fiancĂ© Eric Johnson, Jessica Simpson has lost more than 60 lbs. – and she doesn't need to wear anything more revealing than a pair of boot-cut jeans to prove it.

Dressed down in denim and a hot pink blazer, the new mom, 32, showed off her slim figure Saturday at a Tampa, Fla., event for her fashion line, the Jessica Simpson Collection. Two days prior, the Weight Watchers spokesperson posted a sneak peek on Twitter of the commercial she shot for the weight-loss company.

For Simpson, getting back into shape after giving birth hasn't been as easy as whipping up her favorite pregnancy craving, macaroni and cheese.

"My body is not bouncing back like a supermodel," she said in September, the same month she first debuted her post-baby body. "I'm just your everyday woman who is trying to feel good and be healthy for her daughter, her fiancé and herself."

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EU drug regulator OKs Novartis' meningitis B shot

LONDON (AP) — Europe's top drug regulator has recommended approval for the first vaccine against meningitis B, made by Novartis AG.

There are five types of bacterial meningitis. While vaccines exist to protect against the other four, none has previously been licensed for type B meningitis. In Europe, type B is the most common, causing 3,000 to 5,000 cases every year.

Meningitis mainly affects infants and children. It kills about 8 percent of patients and leaves others with lifelong consequences such as brain damage.

In a statement on Friday, Andrin Oswald of Novartis said he is "proud of the major advance" the company has made in developing its vaccine Bexsero. It is aimed at children over two months of age, and Novartis is hoping countries will include the shot among the routine ones for childhood diseases such as measles.

Novartis said the immunization has had side effects such as fever and redness at the injection site.

Recommendations from the European Medicines Agency are usually adopted by the European Commission. Novartis also is seeking to test the vaccine in the U.S.

Read More..

Boy, 14, sexually assaulted 65-year-old woman at store, police say



A 14-year-old California boy was arrested Thursday night in connection with the attempted murder, kidnapping and sexual assault of a 65-year-old woman.


Officers found the woman bound by duct tape in a ditch near Hiddenbrooke Parkway and Interstate Highway 80 around 6 p.m. Thursday, according to the Bay City News Service.


Police said the victim was kidnapped at gunpoint in front of a retail store and was forced to drive to a location five miles away where she was physically and sexually assaulted.


The suspect then fled in the victim's minivan and called one of her family members, demanding money for her safe return.


Detectives located the suspect after he returned to the area. He was found with a replica handgun and the victim's minivan, police said.


The teen has been booked into Solano County Juvenile Hall.


ALSO:

Only 31% of California students are physically fit


Laguna Beach to punish parents for teen drinking


L.A. deputy charged in slaying, faces 75-year term if convicted


-- Wesley Lowery


Follow Wesley Lowery on Twitter and Google+.


Read more


here: http://www.sacbee.com/2012/11/16/4991207/teen-arrested-in-vallejo-elderly.html#storylink=cpy



Read More..

2nd Tunisian Man Held in Embassy Attack Dies





TUNIS, Tunisia (AP) — A prisoner who had been on a two-month hunger strike after his arrest on charges of attacking the United States Embassy in Tunis in September died on Saturday, his lawyer said. He was the second person on a hunger strike detained in the attack, incited by an anti-Muslim film produced in the United States, to die this week.




The prisoner, Mohammed Bakhti, a prominent member of the ultraconservative Muslim Salafi movement, was admitted to intensive care days earlier after complications resulting from his hunger strike, said the lawyer, Abdel-Basset Ben Mbarek. Mr. Mbarek also represented the other detainee, Bachir al-Gholi, who died Thursday after a heart attack brought on by his own hunger strike.


The two men had proclaimed their innocence, and Mr. Mbarek accused the authorities of responding too late to their grave condition.


Since the fall of Tunisia’s hard-line secular dictatorship in January 2011, there has been a resurgence of conservative Islamic movements in Tunisia. Salafis have attacked art galleries and cultural institutes for perceived insults to Islam, culminating in the Sept. 14 assault on the United States Embassy over the amateur film, which insulted the Prophet Muhammad.


Security forces killed four people in the attack. The area around the embassy was damaged, and an American school was gutted.


About 425 suspects were rounded up in the aftermath of the attack, with 225 remaining in custody, according to Justice Minister Noureddine Bhiri.


The minister, speaking at a news conference on Friday, said he regretted the death of Mr. Gholi and deplored the use of hunger strikes as a protest. He said the death would be investigated.


The Tunisian League for the Defense of Human Rights has called for an independent investigation.


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President Obama Perfects the McKayla Maroney Scowl















11/17/2012 at 01:45 PM EST








Pete Souza/The White House/Getty


Heads up, America: the President is not impressed.

During the U.S. women's gymnastics team's visit to the White House on Thursday, president Barack Obama posed with McKayla Maroney, pulling the apathetic expression that made Maroney an Internet sensation during the Summer Games in London.

Afterwards, the gold medalist, 16 – who's been mimicked by everyone from Maria Menounos to, perhaps inadvertently, Prince William – seemed uncharacteristically, well, impressed.

She Tweeted: "Did I just do the Not Impressed face with the President?"

For those who don't recall, the scowl that sparked a thousand memes originated after Maroney's faulty landing during the individual women's gymnastics vault event in London.

Read More..

EU drug regulator OKs Novartis' meningitis B shot

LONDON (AP) — Europe's top drug regulator has recommended approval for the first vaccine against meningitis B, made by Novartis AG.

There are five types of bacterial meningitis. While vaccines exist to protect against the other four, none has previously been licensed for type B meningitis. In Europe, type B is the most common, causing 3,000 to 5,000 cases every year.

Meningitis mainly affects infants and children. It kills about 8 percent of patients and leaves others with lifelong consequences such as brain damage.

In a statement on Friday, Andrin Oswald of Novartis said he is "proud of the major advance" the company has made in developing its vaccine Bexsero. It is aimed at children over two months of age, and Novartis is hoping countries will include the shot among the routine ones for childhood diseases such as measles.

Novartis said the immunization has had side effects such as fever and redness at the injection site.

Recommendations from the European Medicines Agency are usually adopted by the European Commission. Novartis also is seeking to test the vaccine in the U.S.

Read More..